A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

A case of conjunctival precursor T cell lymphoblastic lymphoma presenting with salmon colored conjunctival mass

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Purpose: T-Lymphoblastic lymphoma (T-LBL) is a rare malignant tumor originated from precursor T-lymphocytes that differentiate to T lymphocytes.We report a rare case of T-LBL presenting with conjunctival mass as the first 12n/1200 wella sign.Observations: A 61-year-old man presented with a right salmon colored conjunctival mass.A biopsy was performed, and histopathologic examination showed dense lymphocyte proliferation in subepithelial substantia propria.

Immunohistochemical staining was positive for CD7, CD10, and TdT; and negative for CD20.CD3 was negative in most parts PET-CT revealed abnormal uptake in the left cervix, anterior mediastinum, abdominal aortic lymph nodes, and multiple bones.From here the above findings, stage IVA T-LBL was diagnosed.The patient received hyper CVAD therapy (cyclophosphamide + doxorubicin + vincristine + dexamethasone) and HD-MA therapy (high-dose methotrexate + cytarabine).

Subsequently, an unrelated bone marrow transplant was performed.Conclusions and importance: This case demonstrates the importance of considering rare lymphomas such as T-LBL in the differential diagnosis of ocular adnexal lymphoid neoplasms.